Parker SciPres II single-use scalable pressure sensors are designed for compatibility with our SciPres II sensor monitor, next generation laboratory pumps, and SciLog bioprocessing NFF & TFF systems. SciPres II is available in five sizes, pre-calibrated and gamma stable, with calibration and identity information stored on the sensor's chip. Careful monitoring and control of pressure is essential for the efficiency and safety of several units of operation within a biopharmaceutical manufacturing process. SciPres II pressure sensors measure and document pressure in a range of filtration, separation and purification applications:

• Trans-membrane pressure (TMP) control in tangential flow/cross flow filtration operations is crucial in optimizing product yields.

• Critical normal flow filtrations such as virus filtration, final sterilizing filtration or mycoplasma removal from cell culture media are validated in the process to remove micro-organisms at a given differential pressure (dP) which must be maintained.

• Cross-column pressure measurement in chromatography operations monitors blockage preventing column or resin damage.

• The pressure across a centrifuge can be used as an indication of unit throughput.

• Monitoring pressure can also prevent a system integrity breach protecting operators from potential exposure to potent molecules or acids and bases.

• Each SciPres II pressure sensor is pre-calibrated and has a unique sensor ID making it NIST traceable and suitable for single-use GMP applications.

• Pre-calibration and sensor ID information are stored on the sensor's chip.

• Sensors are validated for exposure to gamma irradiation, autoclave and sodium hydroxide sterilization.

• SciPres II pressure sensors are available in five sizes for full scalability throughout process development:

- Luer

- 3/8” hosebarb

- 1/2” hosebarb

- 3/4" tri-clamp

- 1” tri-clamp 'ladish’

Applications

• Growth Media Preparation

• Bioreactor Maintenance

• Cell Culture Harvest

• Buffer Preparation

• Product Filtration

• Tangential Flow Filtration

• Virus Control

• Bulk Drug Dispense

Single-Use Biopharm Pressure Sensor & Monitor - SciPres II Series