SciLog TFF Automated Tangential Flow Filtration Systems - EMEA | ParkerGB

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SciLog TFF Automated Tangential Flow Filtration Systems - EMEA

SciLog TFF Automated Tangential Flow Filtration Systems - EMEA

SciLog® TFF Systems are automated bioprocessing systems for tangential flow filtration applications such as diafiltration and concentration (ultrafiltration/microfiltration).

Technical Specifications

  • Brand: SciLog
  • Division: Bioscience and Water Filtration Division
  • Industry: Pharmaceuticals, Biopharmaceuticals
  • Application: Tangential Flow Filtration
  • Technology: Filtration
  • Product Type: Automated Single-Use System
  • Product Style: Automated
  • Product Series: SciLog® TFF (EMEA)
  • Materials of Construction: 304L stainless steel framework (316L on request), mobile platform with pharmaceutical grade casters. IPx5
  • Specifications Met: FDA 21 CFR Part 11, EudraLex Annex 11
  • Sensor Connection: 3 x Pressure Sensor Connections (DIN)
  • Sensor Type: SciPres® II Pressure Sensor, SciCon® II Conductivity Sensor
  • Software: SIEMENS S-7 1500 with TIA Portal
  • Pump Type: Active Directory Integration
  • Flow Rate: 0.2 to 83 L/min
  • Maximum Operating Pressure: 4.0 barg
  • Filter Type: Flat Sheet Cassette, Hollow Fibre
  • Accessories Included: FAT and SAT (including training), Certificate of Compliance, System Operations Manual, P&ID and General Arrangement Drawings, Electrical Schematic, Calibration Certificates, Critical Spares List with Manuals or Datasheets, Frame Material Certificates, GAMP Documentation Package including FDS, HDS, SDS
  • Optional Accessories: Servicing, Additional On-site Training, IQ/OQ Documentation Package, IQ/OQ Execution, PQ Package
Safety Warning

Full Product Description

Utilizing single-use assemblies and sensing technology, the system is compatible with any brand of TFF hollow fibre or cassette filters ensuring flexibility to fit Parker's automation capabilities to customer process specifications.

The SciLog® TFF Systems incorporate SciPres® II pressure sensor technology to automatically monitor, adjust and document pressure, flow rates and transmembrane pressure to prevent extreme pressure over the membrane. This, in turn, safeguards the filter to maximize its lifetime and efficiency.

In conjunction with Parker's single-use manifolds, SciLog® TFF Systems can be configured to achieve flow rates of between 0.33 and 83 L/min with options of peristaltic and diaphragm feed pumps available.

Features and Benefits

• Capable of processing at flow rates of 0.33-83 L/min depending on format
• Operating pressure up to 4 barg
• Suitable for ultrafiltration and microfiltration applications and comes standard with diafiltration capabilities
• Configurable recipe creation to control the process either in discrete steps or batch made
• Touch-screen HMI with intuitive graphical interface
• User-friendly workflow
• Siemens TIA Portal based control system
• Fully programmable alarms and interlocks
• FDA 21 CFR Part 11 and EudraLex Annex 11 Compliance
• Easy integration into DCS/SCADA systems
• Direct connection to scales and mixers
• User access level control via local or Active Directory
• Minimizes retentate vessel size using batch fed concentration mode
• Designed with optimal cleanability in mind

Manifold Design

Parker's single-use manifolds are designed and manufactured to optimize the filtration process and minimize product loss. Manifolds can be supplied gamma irradiated, and integrated with single-use components from a broad range of suppliers to ensure a seamless process fit.

Control System

SciLog® TFF systems can be operated as a standalone system with process control, data collection and user levels remaining on the local system. They can also be operated connected to DCS systems using OPC or Ethernet IP communication protocols for Active Directory and parameter monitoring.

Related Documents

Literature and Reference Materials
[DATASHEET]-SciLog TFF System EMEA
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